California plane crash: Two people killed after aircraft hits commercial building in Fullerton, Orange County

Emergency services have rushed to a commercial building in California after a plane crashed into a structure near Disneyland.

Two people are confirmed dead, and 18 others have been injured after the small plane crashed through the rooftop of a commercial building in southern California.

The crash happened in the Orange County city of Fullerton, Fullerton police spokesperson Kirsty Wells said.

Firefighters and police arrived on the scene and battled a blaze that broke out, and evacuated surrounding businesses, Ms Wells said.

Video has emerged on social media showing the moment the plane hit the building, bursting into flames.

The security camera footage from Rucci Forge, a wheel manufacturer across the street, shows a fiery explosion and a large plume of black smoke as the plane appeared to dive into the building tilted on its side.

The fire damaged the warehouse, which appeared to contain sewing machines and textile stock. The building was occupied by Michael Nicholas Designs, a furniture upholstery manufacturer, according to a sign on a door.

Another video posted to Instagram appears to show a person inside the warehouse running with their arm on fire, as a blaze broke out following the crash.

Ten people were taken to the hospital, while eight were treated and released at the scene, police said.

It was not immediately known what type of plane it was or whether those injured were in the aircraft or on the ground, Ms Wells said.

The flight-tracking website FlightAware shows a four-seat, single-engine aircraft crashed about a minute after takeoff.

The plane crashed near the Fullerton Municipal Airport, a general aviation airport in Orange County that is about 10km from Disneyland.

Fullerton is a city of about 140,000 people some 40km southeast of Los Angeles.

- With AAP